Tea Polyphenol (−)-Epigallocatechin-3-Gallate: A New Trapping Agent of Reactive Dicarbonyl Species
نویسندگان
چکیده
منابع مشابه
Green Tea Polyphenol Epigallocatechin-3-Gallate Attenuates Behavioral Abnormality in Hemi-Parkinsonian Rat
Background: Epigallocatechin gallate (EGCG), a major constituent of green tea, has been introduced as a potent free radical scavenger and can effectively reduce free radical-induced lipid peroxidation. Since free radical injury plays an important role in neuronal damage in Parkinson’s disease (PD), this study examined whether EGCG administration would reduce functional asymmetry in an experimen...
متن کاملAnxiolytic properties of green tea polyphenol (-)-epigallocatechin gallate (EGCG).
Naturally occurring polyphenols are potent antioxidants. Some of these compounds are also ligands for the GABA(A) receptor benzodiazepine site. This feature endows them with sedative properties. Here, the anxiolytic activity of the green tea polyphenol (-)-epigallocatechin gallate (EGCG) was investigated after acute administration in mice, using behavioral tests (elevated plus-maze and passive ...
متن کاملAntimicrobial potential of epigallocatechin-3- gallate (EGCG): a green tea polyphenol
The compounding problem of microbial resistance has become a global threat nowadays and demands urgent attention. Given the limited number of clinically proven drugs available, reversion towards compounds from natural resources have become renewed source of interest. Utilization of novel and potent antimicrobial agents with different targets can act as accessories to antibiotic therapy. Conside...
متن کاملCorrection: Epigallocatechin-3-Gallate (EGCG), a Green Tea Polyphenol, Stimulates Hepatic Autophagy and Lipid Clearance
Epigallocatechin gallate (EGCG) is a major polyphenol in green tea that has been shown to have anti-inflammatory, anti-cancer, anti-steatotic effects on the liver. Autophagy also mediates similar effects; however, it is not currently known whether EGCG can regulate hepatic autophagy. Here, we show that EGCG increases hepatic autophagy by promoting the formation of autophagosomes, increasing lys...
متن کاملThe main green tea polyphenol epigallocatechin-3-gallate counteracts semen-mediated enhancement of HIV infection.
Peptide fragments, derived from prostatic acidic phosphatase, are secreted in large amounts into human semen and form amyloid fibrils. These fibrillar structures, termed semen-derived enhancer of virus infection (SEVI), capture HIV virions and direct them to target cells. Thus, SEVI appears to be an important infectivity factor of HIV during sexual transmission. Here, we are able to demonstrate...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chemical Research in Toxicology
سال: 2007
ISSN: 0893-228X,1520-5010
DOI: 10.1021/tx700190s